Empowar study question
Does metformin reduce excess birthweight in offspring of pregnant women with a raised BMI?
The purpose of this study is to see if giving a tablet called metformin to women who start pregnancy with a raised BMI during their pregnancy improves the mother’s and baby’s health. We know that having a raised BMI during pregnancy may cause the baby to grow too much in the womb. It may also cause other pregnancy complications. If you agree to take part in the study we give you either real metformin or dummy (placebo) tablets. We will look at the weight of your baby at birth and measure the baby’s body fat percentage. We will also look at your health during the pregnancy and the baby’s health after he/she is born. We will also ask if you would like to participate in some other studies looking in more detail at how metformin works in pregnancy.
Metformin is a tablet recommended for use in pregnancy for women who develop pregnancy diabetes. We know it is not harmful to take during pregnancy. The study is not about testing the safety of metformin on pregnant ladies but about whether it works at reducing the risks associated with being pregnant and having a high BMI.
EMPOWaR is funded by the Efficacy and Mechanism Evaluation programme (www.eme.ac.uk <http://www.eme.ac.uk/>), which itself is funded by the MRC and NIHR, with contributions from the CSO in Scotland, NISCHR in Wales and the HSC R&D, Public Health Agency, Northern Ireland. It is managed by the NIHR Evaluation, Trials and Studies Coordinating Centre (NETSCC), based at the University of Southampton which is managed by NIHR.
The views and opinions expressed therein are those of the investigators and do not necessarily reflect those of the MRC, NHS, NIHR or the Department of Health.
Below are links to press articles about the study that involve the use of metformin and pregnancy, which may be of interest to you.
Press articles about the study
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